Chronic Liver Failure

Chronic liver failure is a serious condition in which the liver gradually loses its ability to function properly. Specialized medical attention is required, as the liver plays a crucial role in detoxifying the body, producing essential proteins, and regulating metabolism.

Chronic liver failure (CLF), also known as end-stage liver disease, develops over months or years due to prolonged liver damage. The most common cause is cirrhosis, where liver tissue is gradually replaced by scar tissue, impairing function.

Symptoms of chronic liver failure includes:

Persistent jaundice
Fluid accumulation in the abdomen (ascites)
Muscle wasting and weight loss
Frequent infections
Mental confusion (hepatic encephalopathy).

Chronic liver failure is diagnosed through blood tests, imaging, and sometimes liver biopsy.

Treatment focuses on slowing disease progression and managing complications:

Lifestyle changes – avoiding alcohol and following a healthy diet.
Medications to manage symptoms and prevent complications.
Paracentesis to remove excess fluid from the abdomen.
Liver transplantation – the only curative option for end-stage liver failure.

At Karolinska University Hospital, our experienced team can provide comprehensive diagnosis, treatment, and rehabilitation.